[2,4-bis(Phenylmethoxy)-5-pyrimidinyl]-boronic acid

[2,4-bis(Phenylmethoxy)-5-pyrimidinyl]-boronic acid - Names and Identifiers

Name	[2,4-bis(Phenylmethoxy)-5-pyrimidinyl]-boronic acid
Synonyms	AKOS BRN-0093 RARECHEM AH PB 0010 2,4-Bis(Benzyloxy)Pyrimidine-5 2,4-Dibenzyluracil-5-boronic acid 2,4-Di(benzyloxy)pyrimidine-5-boronic acid 2,4-BIS(BENZYLOXY)PYRIMIDINE-5-BORONIC ACID 2,4-Bis(Benzyloxy)Pyrimidin-5-Ylboronic Acid 2,4-Bis-(benxyloxy)pyrimidine-5-boronic acid [2,4-bis(benzyloxy)pyrimidin-5-yl]boronic acid [2,4-bis(Phenylmethoxy)-5-pyrimidinyl]-boronic acid [2,4-BIS(PHENYLMETHOXY)-5-PYRIMIDINYL]-BORONIC ACID
CAS	70523-24-9
InChI	InChI=1/C18H17BN2O4/c22-19(23)16-11-20-18(25-13-15-9-5-2-6-10-15)21-17(16)24-12-14-7-3-1-4-8-14/h1-11,22-23H,12-13H2

[2,4-bis(Phenylmethoxy)-5-pyrimidinyl]-boronic acid - Physico-chemical Properties

Molecular Formula	C18H17BN2O4
Molar Mass	336.15
Density	1.3g/cm³
Melting Point	88-91℃
Boling Point	600.4°C at 760 mmHg
Flash Point	316.9°C
Vapor Presure	2.88E-15mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.627

[2,4-bis(Phenylmethoxy)-5-pyrimidinyl]-boronic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
HS Code	29310095
Hazard Note	Irritant

[2,4-bis(Phenylmethoxy)-5-pyrimidinyl]-boronic acid - Introduction

[2,4-bis(Phenylmethoxy)-5-pyrimidinyl]-boronic acid is an organic compound whose chemical formula is C17H14BNO4. It is a white or off-white crystalline solid, soluble in some organic solvents, such as dimethyl sulfoxide and methylene chloride.

This compound has a wide range of applications in the field of medicine. It is used as an intermediate in pharmaceuticals for the synthesis of biologically active compounds. It can be used in drug development to design and synthesize compounds with anti-cancer, anti-viral and anti-bacterial activities.

The method for preparing [2,4-bis(Phenylmethoxy)-5-pyrimidinyl]-boronic acid is to react 2,4-bibenzyloxypyrimidine with a boronic ester. A common preparation method is to dissolve 2,4-bibenzyloxypyrimidine in dimethyl sulfoxide, add triphenylphosphine and tetrabutylammonium chloride, and then add the boronic ester. After the reaction was carried out, the product was obtained by washing with ammonium chloride brine and freeze-drying.

Regarding safety information,[2,4-bis(Phenylmethoxy)-5-pyrimidinyl]-boronic acid should take appropriate safety measures when operating. It may be irritating to the eyes, skin and respiratory tract, so direct contact should be avoided during operation. It is necessary to operate in a well-ventilated area and use appropriate protective equipment, such as laboratory gloves and breathing masks.

Last Update：2024-04-09 20:49:11